Use guile 2.2. (That's the version MacPorts has today.)
--- configure.in.orig	2013-07-17 15:12:38.000000000 -0500
+++ configure.in	2022-03-23 22:00:42.000000000 -0500
@@ -70,7 +70,7 @@
 # fi
 
 # http://www.gnu.org/software/guile/manual/html_node/Autoconf-Macros.html
-PKG_CHECK_MODULES([GUILE], [guile-2.0])
+PKG_CHECK_MODULES([GUILE], [guile-2.2])
 AC_SUBST(GUILE_CFLAGS)
 AC_SUBST(GUILE_LIBS)